A serine-threonine kinase that contains a C2 DOMAIN and PLECKSTRIN HOMOLOGY DOMAIN. It also has activity as a GTPASE-ACTIVATING PROTEIN for RAC1 PROTEIN and CDC42 PROTEIN. It functions as a negative regulator of CELL PROLIFERATION and NEOPLASTIC CELL TRANSFORMATION and is commonly fused with cellular abl protein to form BCR-ABL FUSION PROTEINS in PHILADELPHIA CHROMOSOME positive LEUKEMIA patients.
Inga svenska synonymer finns.
Proto Oncogene Proteins c bcr — c-bcr, Proto-Oncogene Proteins — Proto-Oncogene Protein c-bcr — Proto Oncogene Protein c bcr — c-bcr, Proto-Oncogene Protein — Breakpoint Cluster Region Protein — c-bcr Proteins — c bcr Proteins — c-bcr Proto-Oncogene Proteins — Proto-Oncogene Proteins, c-bcr — c bcr Proto Oncogene Proteins — bcr Proto-Oncogene Proteins — Proto-Oncogene Proteins, bcr — bcr Proto Oncogene Proteins — Proto-Oncogene Protein bcr — Proto Oncogene Protein bcr