Receptor, PAR-2

PAR-2-receptor

Engelsk definition

A G-protein-coupled, proteinase-activated receptor that is expressed in a variety of tissues including ENDOTHELIUM; LEUKOCYTES; and the GASTROINTESTINAL TRACT. The receptor is activated by TRYPSIN, which cleaves off the N-terminal peptide from the receptor. The new N-terminal peptide is a cryptic ligand for the receptor. The uncleaved receptor can also be activated by the N-terminal peptide present on the activated THROMBIN RECEPTOR and by small synthetic peptides that contain the unmasked N-terminal sequence.

Svenska synonymer

Receptor, PAR-2

Engelska synonymer

Receptor, PAR 2 Trypsin Receptors Receptors, Trypsin Trypsin Receptor PAR2 Receptor Receptor, PAR2 Proteinase Activated Receptor 2 Protease-Activated Receptor 2 Protease Activated Receptor 2 Receptor 2, Protease-Activated Receptor, Trypsin PAR-2 Receptor PAR 2 Receptor