Små, katjoniska peptider som hos de flesta arter utgör en viktig del av det tidiga, medfödda och framkallade försvaret mot angripande mikroorganismer. Hos djur finns de på slemhinnor, i fagocytkorn oc h på kroppsytorna. Också insekter och växter har dessa peptider. Gruppen omfattar bl a defensiner, protegriner, takyplesiner och tioniner.
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Inga svenska synonymer finns.
Cationic Peptides, Antimicrobial — Peptides, Antimicrobial Cationic — Microbicidal Cationic Proteins — Cationic Proteins, Microbicidal — Proteins, Microbicidal Cationic — Cationic Antimicrobial Peptides — Antimicrobial Peptides, Cationic — Peptides, Cationic Antimicrobial — Cationic Host Defense Peptides — Cationic Antimicrobial Peptide — Antimicrobial Peptide, Cationic — Peptide, Cationic Antimicrobial — Amphipathic Cationic Antimicrobial Peptides — Host Defense Peptides — Defense Peptides, Host — Peptides, Host Defense — Host Defense Peptide — Defense Peptide, Host — Peptide, Host Defense