Focal Adhesions

Fokala vidhäftningar

Svensk definition

Förankringsställen mellan celler och ett icke-cellulära substrat. De består av speciella områden på plasmamembranet, där knippen av mikrofilament slutar och fäster vid transmembranlänkningar, integriner, vilka i sin tur med sina extracellulära domäner förenas med yttre matrisproteiner.

Engelsk definition

An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.

Svenska synonymer

Fokaladhesion

Engelska synonymer

Adhesion, Focal Adhesions, Focal Focal Adhesion Focal Contacts Contact, Focal Contacts, Focal Focal Contact Adhesion Plaques Adhesion Plaque Plaque, Adhesion Plaques, Adhesion Cell-Matrix Adherens Junctions Adherens Junction, Cell-Matrix Adherens Junctions, Cell-Matrix Cell Matrix Adherens Junctions Cell-Matrix Adherens Junction Junction, Cell-Matrix Adherens Junctions, Cell-Matrix Adherens