Svensk definition
Ett peptidas av cysteintyp som är klorberoende och har sin maximala verkan vid sura pH-värden. Vid neutralt pH polymeriserar det estrar, akryl- och dipeptidamider. EC 3.4.14.1. Syn. katepsin C.
Cathepsin C
Katepsin C
Engelsk definition
A papain-like cysteine protease that has specificity for amino terminal dipeptides. The enzyme plays a role in the activation of several pro-inflammatory serine proteases by removal of their aminoterminal inhibitory dipeptides. Genetic mutations that cause loss of cathepsin C activity in humans are associated with PAPILLON-LEFEVRE DISEASE.
Svenska synonymer
Dipeptydylpeptidas I
Engelska synonymer
Dipeptidyl Peptidase I — Dipeptidyl Transferase — Dipeptidyl Aminopeptidase I