Långtidsverkande, spänningsreglerade kalciumkanaler i såväl retningsbara som icke-retningsbara vävnader. De är ansvariga för sammandragningen av hjärtmuskel och vaskulär glatt muskulatur. L-typ-kanale n består av fem underenheter (alfa-1, alfa-2, beta, gamma och delta). Alfa-1-enheten är är bindningsplatsen för kalciumbaserade antagonister. Dihydropyridinbaserade kalciumantagonister används som mar körer för dessa bindningsställen.
Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and non-excitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
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Calcium Channels, L Type — L-Type Calcium Channels — L Type Calcium Channels — L-Type VDCC — L Type VDCC — VDCC, L-Type — Long-Lasting Calcium Channels — Calcium Channels, Long-Lasting — Long Lasting Calcium Channels — L-Type Calcium Channel — Calcium Channel, L-Type — L Type Calcium Channel — L-Type Voltage-Dependent Calcium Channels — L Type Voltage Dependent Calcium Channels — L-Type Voltage-Dependent Calcium Channel — L Type Voltage Dependent Calcium Channel — Long-Lasting Calcium Channel — Calcium Channel, Long-Lasting — Channel, Long-Lasting Calcium — Long Lasting Calcium Channel — Receptors, Dihydropyridine — L-Type VDCC alpha-1 Subunit — L Type VDCC alpha 1 Subunit — Dihydropyridine Receptor — Receptor, Dihydropyridine — Dihydropyridine Receptors — L-Type VDCC delta Subunit — L Type VDCC delta Subunit — L-Type VDCC alpha-2 Subunit — L Type VDCC alpha 2 Subunit — L-Type VDCC beta Subunit — L Type VDCC beta Subunit — L-Type VDCC gamma Subunit — L Type VDCC gamma Subunit