Svensk definition
Akut, autoimmun nervinflammation orsakad av ett T-cellförmedlat, cellulärt immunsvar riktat mot myelin i perifera nerver och nervrötter. Sjukdomsförloppet föregås ofta av en virus- eller bakterieinfektion, kirurgiskt ingrepp, immunisering, lymfom eller exponering för giftiga ämnen. Vanliga kliniska tecken är tilltagande trötthet, känselbortfall och förlust av djupa senreflexer. Även försvagning av andningsmuskulaturen och bristande autonom funktion kan förekomma.
Engelsk definition
An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
Svenska synonymer
AIDP — Akut inflammatorisk polyradikuloneuropati — Akut autoimmun neuropati — Akut inflammatorisk demyeliniserande polyneuropati
Engelska synonymer
Guillain Barre Syndrome — Syndrome, Guillain-Barre — Guillaine-Barre Syndrome — Guillaine Barre Syndrome — Syndrome, Guillaine-Barre — Guillain-Barré Syndrome — Guillain Barré Syndrome — Guillain-Barré Syndromes — Syndrome, Guillain-Barré — Landry-Guillain-Barre Syndrome — Landry Guillain Barre Syndrome — Syndrome, Landry-Guillain-Barre — Acute Autoimmune Neuropathy — Acute Autoimmune Neuropathies — Autoimmune Neuropathies, Acute — Autoimmune Neuropathy, Acute — Neuropathy, Acute Autoimmune — Acute Infectious Polyneuritis — Infectious Polyneuritis, Acute — Polyneuritis, Acute Infectious — Guillain-Barre Syndrome, Familial — Familial Guillain-Barre Syndrome — Familial Guillain-Barre Syndromes — Guillain Barre Syndrome, Familial — Guillain-Barre Syndromes, Familial — Syndrome, Familial Guillain-Barre — Acute Inflammatory Demyelinating Polyneuropathy — Inflammatory Polyneuropathy Acute — Polyneuropathy Acute, Inflammatory — Acute Inflammatory Demyelinating Polyradiculoneuropathy — Acute Inflammatory Polyneuropathy — Acute Inflammatory Polyneuropathies — Inflammatory Polyneuropathies, Acute — Inflammatory Polyneuropathy, Acute — Polyradiculoneuropathy, Acute Inflammatory — Acute Inflammatory Polyradiculoneuropathies — Inflammatory Polyradiculoneuropathies, Acute — Polyradiculoneuropathies, Acute Inflammatory — Polyneuropathy, Inflammatory Demyelinating, Acute — Demyelinating Polyradiculoneuropathy, Acute Inflammatory — Polyneuropathy, Acute Inflammatory — Polyradiculoneuropathy, Acute Inflammatory Demyelinating — Inflammatory Demyelinating Polyradiculoneuropathy, Acute — Acute Inflammatory Polyradiculoneuropathy