Ett flerfunktionsmitokondrieenzym tillhörande gruppen cytokrom P450-enzym som katalyserar omvandlingen av kortikosteron till 18-hydroxikortikosteron och den därpå följande konverteringen av 18-hydroxikortikosteron till aldosteron. EC 1.14.99.-.
A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.
Aldosteronsyntas
Cytochrome P 450 CYP11B2 — P450c11AS — Steroid 18-Hydroxylase — Steroid 18 Hydroxylase — Aldosterone Synthase — Cytochrome P-450c11AS — Cytochrome P 450c11AS — Aldosynthase — Cytochrome P450Aldo — CYP 11B2 — Cytochrome P450 11B2 — CYP11B2 — Aldosterone Synthase Cytochrome P-450 — Corticosterone 18-monooxygenase — 18-monooxygenase, Corticosterone — Corticosterone 18 monooxygenase — Corticosterone 18-hydroxylase — 18-hydroxylase, Corticosterone — Corticosterone 18 hydroxylase