Svensk definition
Differentieringsantigener på ett flertal cellstammar, inklusive lymfoida och lymfoblastoida. Deras primära uppgift är att reglera perifera immunsvar, vilket åstadkoms genom att apoptos sätts igång.
fas Receptor
fas-receptor
Engelsk definition
A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.
Svenska synonymer
CD95-antigener — fas-antigen
Engelska synonymer
Receptor, fas — fas Antigen — fas Antigens — APO-1 Antigen — APO 1 Antigen — CD95 Antigen — TNFRSF6 Receptor — Receptor, TNFRSF6 — Antigens, CD95 — Receptors, fas — fas Receptors — Tumor Necrosis Factor Receptor Superfamily, Member 6 — Fas Cell Surface Death Receptor — CD95 Antigens