Receptors, Death Domain


Engelsk definition

A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.

Svenska synonymer

Dödsreceptorer DR-familjreceptorer

Engelska synonymer

Death Receptors Receptors, DR Family DR Family Receptors Death Domain Receptors Death Receptor Receptor, Death Receptors, Death Domain Family