Receptors, Cytoplasmic and Nuclear

Cytoplasmatiska och nukleära receptorer

Svensk definition

Proteiner i cytoplasman eller cellkärnan som specifikt binder signalmolekyler och utlöser förändringar som påverkar hur celler beter sig. De största grupperna är steroidhormonreceptorerna, som normalt finns i cytoplasman, och sköldkörtelhormonreceptorerna, som normalt finns i cellkärnan. Receptorer, till skillnad från enzym, katalyserar vanligtvis inte kemiska förändringar i sina ligander.

Engelsk definition

Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.

Svenska synonymer

Nukleära receptorer Kärnreceptorer Cytoplasmiska receptorer Cytoplasmreceptorer Intracellulära membranreceptorer Nukleära hormonreceptorer

Engelska synonymer

Nuclear and Cytoplasmic Receptors Receptors, Cytosol and Nuclear Receptors, Cytosolic and Nuclear Receptors, Nuclear and Cytoplasmic Cytoplasmic and Nuclear Receptors Cytosol and Nuclear Receptors Cytosolic and Nuclear Receptors Receptors, Cytoplasmic Cytoplasmic Receptor Receptor, Cytoplasmic Cytoplasmic Receptors Receptors, Nuclear Nuclear Receptor Receptor, Nuclear Nuclear Receptors Hormone Receptors, Nuclear Receptors, Nuclear Hormone Nuclear Hormone Receptor Hormone Receptor, Nuclear Receptor, Nuclear Hormone Nuclear Hormone Receptors Hormone Receptors, Cytoplasmic Receptors, Cytoplasmic Hormone Cytoplasmic Hormone Receptors Receptors, Intracellular Membrane Membrane Receptors, Intracellular Intracellular Membrane Receptors