Glykoproteiner med hög molekylvikt som uteslutande visar sig på ytan av leukocyter och deras hemopoetiska stamceller. CD45-familjen b estår av ett flertal medlemmar som alla är produkter av en enda ge n. Uttryck av CD45 är nödvändigt för signallering via T-cellreceptorn.
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.
L-CA antigener — CD45R0 antigener — CD45RB antigener — CD45RA antigener
Antigens, Leukocyte Common — CD45 Antigens — Antigens, CD45 — Protein Tyrosine Phosphatase, Receptor Type, C — L-CA Antigens — Antigens, L-CA — L CA Antigens — Leukocyte Common Antigen — Antigen, Leukocyte Common — CD45 Antigen — Antigen, CD45 — T200 Antigens — Antigens, T200 — CD45RO Antigens — Antigens, CD45RO — CD45R0 Antigens — Antigens, CD45R0 — CD45RB Antigens — Antigens, CD45RB — CD45RCAntigens — B220 Antigens — Antigens, B220 — CD45R Antigens — Antigens, CD45R — B220 Antigen — Antigen, B220 — CD45RA Antigens — Antigens, CD45RA — 2H4 Antigens — Antigens, 2H4