Genes, Tumor Suppressor

Tumörsuppressorgener

Svensk definition

Gener som blockerar uttryck av den cancerogena fenotypen. Deras normala uppgift är att hämma celltillväxt. När dessa suppressorgener inaktiveras eller saknas, faller en barriär för normal celltillväxt bort, och ohämmad tillväxt blir möjlig.

Engelsk definition

Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.

Svenska synonymer

Antionkogener Cancersuppressorgener Recessiva onkogener Metastassuppressorgener Anti-onkogener

Engelska synonymer

Gene, Tumor Suppressor Tumor Suppressor Gene Antioncogenes Antioncogene Emerogenes Emerogene Genes, Onco-Suppressor Gene, Onco-Suppressor Genes, Onco Suppressor Onco-Suppressor Gene Onco-Suppressor Genes Cancer Suppressor Genes Cancer Suppressor Gene Gene, Cancer Suppressor Suppressor Gene, Cancer Suppressor Genes, Cancer Oncogenes, Recessive Oncogene, Recessive Recessive Oncogene Recessive Oncogenes Anti-Oncogenes Anti Oncogenes Anti-Oncogene Tumor Suppressing Genes Gene, Tumor Suppressing Genes, Tumor Suppressing Tumor Suppressing Gene Genes, Cancer Suppressor Tumor Suppressor Genes Metastasis Suppressor Genes Gene, Metastasis Suppressor Metastasis Suppressor Gene Suppressor Gene, Metastasis Suppressor Genes, Metastasis Genes, Metastasis Suppressor Growth Suppressor Genes Gene, Growth Suppressor Growth Suppressor Gene Suppressor Gene, Growth Suppressor Genes, Growth Genes, Growth Suppressor