Svensk definition
Enzymsystem med två underenheter och som kräver ATP och magnesium för endonukleolytisk verkan. De fungerar inte som ATPaser. De finns i komplex med modifieringsmetylaser med liknande specificitet under EC 2.1.1.72 (DNA-metyltransferas, adeninspecifikt) eller EC 2.1.1.73 (DNA-metyltransferas, cytosinspecifikt). Systemen känner igen specifika, korta DNA-sekvenser och klyver nära, 24 till 27 baser, den igenkända sekvensen för att ge specifika, dubbelsträngade fragment med 5'-fosfatändar. Enzymer från olika mikroorganismer med samma specificitet kallas isoschizomerer. EC 3.1.21.5.
Engelsk definition
Enzyme systems composed of two subunits and requiring ATP and magnesium for endonucleolytic activity; they do not function as ATPases. They exist as complexes with modification methylases of similar specificity listed under EC 2.1.1.72 or EC 2.1.1.73. The systems recognize specific short DNA sequences and cleave a short distance, about 24 to 27 bases, away from the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.5.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
Deoxyribonucleases, Type III Site Specific — Deoxyribonucleases, Type III, Site-Specific — Type III Site Specific Deoxyribonucleases — Type III Site-Specific Deoxyribonucleases — DNA Restriction Enzymes, Type III — Type III Restriction Enzymes — Site-Specific DNase, Type III — Site Specific DNase, Type III — Type III Site Specific DNase — Type III Site-Specific DNase — DNase, Site-Specific, Type III — Restriction Endonucleases, Type III — Deoxyribonucleases, Type III, Site Specific — DNase, Site Specific, Type III