Svensk definition
EC 1.14.99.9
Steroid 17-alpha-Hydroxylase
Steroid-17-alfa-monooxygenas
Engelsk definition
A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
17-alpha-Hydroxylase, Steroid — Steroid 17 alpha-Hydroxylase — 17 alpha-Hydroxylase, Steroid — Steroid 17 alpha Hydroxylase — Steroid-17-Hydroxylase — Steroid 17 Hydroxylase — Steroid 17-Hydroxylase — 17-Hydroxylase, Steroid — Steroid 17-Monooxygenase — 17-Monooxygenase, Steroid — Steroid 17 Monooxygenase — 17,20-Desmolase — 17,20 Desmolase — 17,20-Lyase — 17,20 Lyase — Cytochrome P450(17 alpha) — Steroid 17 alpha-Monooxygenase — 17 alpha-Monooxygenase, Steroid — Steroid 17 alpha Monooxygenase — alpha-Monooxygenase, Steroid 17 — CYP17 — 17 alpha-Hydroxylase — 17 alpha Hydroxylase — P450(c17) — Cytochrome P-450(17-alpha) — 17 alpha-Hydroxylase Cytochrome P-450 — 17 alpha Hydroxylase Cytochrome P 450 — Cytochrome P-450(17 alpha) — 17 alpha-Hydroxyprogesterone Aldolase — 17 alpha Hydroxyprogesterone Aldolase — Aldolase, 17 alpha-Hydroxyprogesterone — alpha-Hydroxyprogesterone Aldolase, 17 — Hydroxyprogesterone Aldolase — Aldolase, Hydroxyprogesterone