Mechlorethamine

Mekloretamin

Svensk definition

Ett biologiskt, akylerande medel som genom sina cytotoxiska egenskaper bildar DNA-addukter och . Vätekloridderivatet används som cellgift vid Hodgkins sjukdom och lymfom.

Engelsk definition

A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Chlormethine Bis(2-chloroethyl)methylamine Mustine Nitrogen Mustard Chlorethazine Methylchlorethamine Cloramin Embichin Mechlorethamine Hydrochloride Hydrochloride, Mechlorethamine Mechlorethamine Hydrochloride N-Oxide Hydrochloride N-Oxide, Mechlorethamine Mechlorethamine Hydrochloride N Oxide N-Oxide, Mechlorethamine Hydrochloride NSC-762 NSC 762 NSC762 Mechlorethamine Oxide Mitomen Mustargen Nitrogranulogen Nitromin NSC-10107 NSC 10107 NSC10107 Caryolysine Mechlorethamine N-Oxide Mechlorethamine N Oxide Nitrogen Mustard N-Oxide N-Oxide, Nitrogen Mustard Nitrogen Mustard N Oxide