Kristalliserande fragment bestående av karboxiändarna av båda de tunga kedjorna, länkade med disulfidbindningar. Fc-fragmenten svarar för antikropparnas effektorfunktioner (komplementfixering, cellmembranbindning och transport genom moderkakan).
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Immunoglobuliner, Fc
Fc Fragments, Immunoglobulin — Fc Fragment — Fragment, Fc — Ig Fc Fragments — Fc Fragments, Ig — Fragments, Ig Fc — Immunoglobulins, Fc Fragment — Fc Fragment Immunoglobulins — Fragment Immunoglobulins, Fc — Fc Immunoglobulins — Immunoglobulin Fc Fragment — Fc Fragment, Immunoglobulin — Immunoglobulins, Fc — Fc Immunoglobulin — Immunoglobulin, Fc — Fc Fragments