Ett utbrett membrantransportprotein, som förekommer i plasmamembranet till olika typer av celler och vävnader, samt i cellkärnemembran, mitokondriemembran och Golgimembran. Det är det vanligaste membrantransportproteinet hos erytrocyterna och utgör 25% av allt protein i erytrocyternas membran. Det bildar dimerer och fungerar som en kanal för transport av bikarbonat genom membranet i utbyte mot klorjoner.
A major integral transmembrane protein of the ERYTHROCYTE MEMBRANE. It is the anion exchanger responsible for electroneutral transporting in CHLORIDE IONS in exchange of BICARBONATE IONS allowing CO2 uptake and transport from tissues to lungs by the red blood cells. Genetic mutations that result in a loss of the protein function have been associated with type 4 HEREDITARY SPHEROCYTOSIS.
Band 3-protein
Erythrocyte Membrane Protein Band 3, Diego Blood Group — Band III Protein — Capnophorin — Erythrocyte Anion Transport Protein — Anion Transport Protein, Erythrocyte — Erythrocyte Membrane Band 3 Protein — Erythrocyte Anion Exchanger — Anion Exchanger, Erythrocyte — Erythrocyte Membrane Anion Transport Protein — AE1 Cl- HCO3- Exchanger — AE1 Cl HCO3 Exchanger — AE1 Anion Exchanger — AE1 Chloride-Bicarbonate Exchanger — AE1 Chloride Bicarbonate Exchanger — Chloride-Bicarbonate Exchanger, AE1 — AE1 Gene Product — SLC4A1 Protein — Band 3 Anion Transport Protein — Solute Carrier Family 4 Member 1 — EPB3 Protein — Protein, EPB3 — Anion Exchanger 1 — Exchanger 1, Anion — CD233 Antigen — Antigen, CD233 — CD233 Antigens — Antigens, CD233 — Solute Carrier Family 4, Anion Exchanger, Member 1 — Protein Band 3 — Band 3 Protein