Arachidonate 12-Lipoxygenase

Arakidonat 12-lipoxygenas

Svensk definition

Ett enzym som katalyserar oxidationen av arakidonsyra till 12-hydroperoxyarakidonat (12-HPETE), som i sin tur genom peroxidas snabbt omvandlas till 12-hydroxy-5,8,10,14-eikosatetraenoat (12-HETE). 12- hydroperoxiderna bildas företrädesvis i blodplättarna. EC 1.13.11.31.

Engelsk definition

An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

12-Lipoxygenase, Arachidonate Arachidonate 12 Lipoxygenase Arachidonic Acid 12-Lipoxygenase 12-Lipoxygenase, Arachidonic Acid Arachidonic Acid 12 Lipoxygenase 12-Lipoxygenase 12 Lipoxygenase