Svensk definition
Autoantikroppar riktade mot olika antigen i cellkärnor, så som DNA, RNA, histoner, sura kärnproteiner eller komplex av sådana molekyler. Antinukleära antikroppar förekommer i systemiska, autoimmuna sj ukdomar, som t ex systemisk lupus erythematosus (SLE), Sjögrens syndrom, skleroderma, polymyosit och blandad bindvävssjukdom.
Engelsk definition
Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.
Svenska synonymer
Anti-DNA-antikroppar — Fluorescerande antinukleära antikroppar
Engelska synonymer
Antinuclear Autoantibody — Autoantibody, Antinuclear — Antinuclear Factors — Antinuclear Antibody — Antibody, Antinuclear — Antinuclear Factor — Factor, Antinuclear — Antinuclear Autoantibodies — Antinuclear Antibodies — Antibodies, Anti-DNA — Anti-DNA Antibodies — Anti DNA Antibodies