NADPH Oxidase 2

Engelsk definition

An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.

Svenska synonymer

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Engelska synonymer

Oxidase 2, NADPH Chronic Granulomatous Disease Protein GP91-PHOX Protein GP91 PHOX Protein CYBB Protein Cytochrome B-245 Beta Chain Cytochrome B 245 Beta Chain NOX2 Protein