Prion Proteins

Prionproteiner

Engelsk definition

Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU.

Svenska synonymer

CD230 antigen — Alternativt prionprotein

Engelska synonymer

PrP Proteins — Fatal Familial Insomnia Protein — Prion Protein — CD230 Antigen — Antigen, CD230 — Creutzfeldt-Jakob Disease Protein — Creutzfeldt Jakob Disease Protein — Major Prion Protein — Prion Protein, Major — Alternative Prion Protein — Prion Protein, Alternative — AltPrP