BTB-POZ Domain

BTB-POZ-domän

Engelsk definition

A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure.

Svenska synonymer

POxvirus och zinkfingerdomän BTB-domän POZ-domän

Engelska synonymer

BTB POZ Domain BTB-POZ Domains POxvirus and Zinc Finger Domain BTB (POZ) Domain Broad-Complex, Tramtrack and Bric a Brac Domain Broad Complex, Tramtrack and Bric a Brac Domain BTB Domain BTB Domains POZ Domain POZ Domains