Beclin-1

Engelsk definition

An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.

Svenska synonymer

ATG-6 protein — GT197 protein

Engelska synonymer

Beclin 1 — Beclin-1 Protein — Beclin 1 Protein — GT197 Protein — ATG-6 Protein — ATG 6 Protein — Coiled-coil Myosin-like Bcl2-interacting Protein — Coiled coil Myosin like Bcl2 interacting Protein — Beclin1 — ATG6 Protein