Abatacept

Abatacept

Engelsk definition

A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.

Svenska synonymer

Belatacept Orencia

Engelska synonymer

CTLA-4-Ig Cytotoxic T Lymphocyte-Associated Antigen 4-Immunoglobulin Cytotoxic T Lymphocyte Associated Antigen 4 Immunoglobulin CTLA4-Ig CTLA4-Ig Immunoconjugate CTLA4 Ig Immunoconjugate Immunoconjugate, CTLA4-Ig CTLA4-Fc BMS224818 BMS-224818 BMS 224818 Belatacept Orencia BMS 188667 BMS-188667 BMS188667 LEA29Y Nulojix