Svensk definition
Ett pyrimidin- och tiazolderiverat cellgift och proteinkinashämmare hos bcr-abl-fusionsproteinkinas. Det används vid behandling av patienter med kronisk myeloid leukemi som är resistent eller intolerant mot imanitib.
Dasatinib
Dasatinib
Engelsk definition
A pyrimidine and thiazole derived ANTINEOPLASTIC AGENT and PROTEIN KINASE INHIBITOR of BCR-ABL KINASE. It is used in the treatment of patients with CHRONIC MYELOID LEUKEMIA who are resistant or intolerant to IMATINIB.
Svenska synonymer
Sprycel
Engelska synonymer
N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide — Sprycel — (18F)-N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide — BMS 354825 — 354825, BMS — BMS354825 — BMS-354825