Interleukin-1 Receptor Accessory Protein

IL-1RAcP

Engelsk definition

A protein that takes part in the formation of active interleukin-1 receptor complex. It binds specifically to INTERLEUKIN-1 and the INTERLEUKIN-1 RECEPTOR TYPE I at the cell surface to form a heterotrimeric complex that brings its cytoplasmic domain into contact with the cytoplasm domain of the TYPE-I INTERLEUKIN-1 RECEPTOR. Activation of intracellular signal transduction pathways from the receptor is believed to be driven by this form of cytoplasmic interaction.

Svenska synonymer

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Engelska synonymer

Interleukin 1 Receptor Accessory Protein IL-1RAcP