Ett transmembranöst, domänbärande matrismetalloproteinas (MMP-16; MTMMP-3). Det syntetiseras som en inaktiv zymogen, vilken aktiveras av proproteinkonvertasers proteolytiska verkan. MMP-16 spelar en direkt roll i spjälkningen av proteiner i den pericellulära omgivningen. Dessutom verkar det indirekt genom att enzymatiskt aktivera proproteinformen av andra matrismetalloproteinaser, så som zymogenformen av MMP-2. EC?
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the proteolytic action of PROPROTEIN CONVERTASES. Matrix metalloproteinase 16 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of other MATRIX METALLOPROTEINASES such as the zymogen of MATRIX METALLOPROTEINASE 2.
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Membrane-Type Matrix Metalloproteinase 3 — Membrane Type Matrix Metalloproteinase 3 — Membrane-Type-3 Matrix Metalloproteinase — Matrix Metalloproteinase, Membrane-Type-3 — Metalloproteinase, Membrane-Type-3 Matrix — MT3-MMP — MMP-X2 Protein — MMP X2 Protein — MMP16 Metalloproteinase — Metalloproteinase, MMP16 — MT3-Matrix Metalloproteinase — MT3 Matrix Metalloproteinase — Membrane-Type 3 Matrix Metalloproteinase — Membrane Type 3 Matrix Metalloproteinase — MMP-16 Metalloproteinase — MMP 16 Metalloproteinase — Metalloproteinase, MMP-16