Konjugering av exogena substanser med olika hydrofila föreningar för bildande av vattenlösliga ämnen som kan utsöndras i urin. Fas 2-modifieringar omfattar glutation, acylering och aminering. Till fas 2-enzymerna hör glutationtransferas och glukuronosyltransferas. Dessa fas 2-reaktioner bryter ned reaktionsprodukterna från fas 1.
The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
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Metabolic Detoxication, Conjugative — Conjugative Metabolic Detoxication — Conjugative Metabolic Detoxications — Detoxication, Conjugative Metabolic — Detoxications, Conjugative Metabolic — Metabolic Detoxications, Conjugative — Phase II Detoxification — Detoxification, Phase II — Detoxifications, Phase II — Phase II Detoxifications — Metabolic Detoxification, Phase II