En underfamilj av mitogenaktiverade proteinkinaser som kommer till utbrett uttryck och spelar en roll vid regleringen av meios, mitos och postmitotiska processer i differentierade celler. Dessa kinaser styrs av en lång rad cellytereceptorer och kan aktiveras av vissa cancerframkallande ämnen. EC 2.7.1.37.
A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.
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Extracellular Signal Regulated MAP Kinases — ERK MAP Kinase — Kinase, ERK MAP — MAP Kinase, ERK — Extracellular Signal-Regulated MAP Kinase — Extracellular Signal Regulated MAP Kinase — MAP Kinases, Extracellular Signal-Regulated — MAP Kinases, Extracellular Signal Regulated — Extracellular Signal-Regulated Kinases — Extracellular Signal Regulated Kinases — Kinases, Extracellular Signal-Regulated — Extracellular Signal-Regulated Kinase — Extracellular Signal Regulated Kinase — Kinase, Extracellular Signal-Regulated — Signal-Regulated Kinase, Extracellular — ERK MAP Kinases