Mitogen-Activated Protein Kinase 1

p42 MAP-kinas

Svensk definition

Ett prolinstyrt serin/treoninproteinkinas som förmedlar signalöverföring från cellytan till kärnan. Aktivering av enzymet genom fosforylering medför att det förflyttas till cellkärnan, där det utövar verkan på specifika transkriptionsfaktorer. p40 MAPK och p41 MAPK är isoforma enzym. EC 2.7.11.24.

Engelsk definition

A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Mitogen Activated Protein Kinase 1 p42 MAPK p42(Mitogen-Activated Protein Kinase) p42(Mapk) Kinase p42 MAP Kinase MAP Kinase, p42 MAPK2 Mitogen-Activated Protein Kinase MAPK2 Mitogen Activated Protein Kinase Extracellular Signal-Regulated Kinase 2 Extracellular Signal Regulated Kinase 2 Mitogen-Activated Protein Kinase 2 Mitogen Activated Protein Kinase 2 MAPK1 Mitogen-Activated Protein Kinase MAPK1 Mitogen Activated Protein Kinase p42(Mapk) MAP Kinase 2