A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
Inga svenska synonymer finns.
Interference, RNA — RNAi — Posttranscriptional Gene Silencing — Gene Silencing, Posttranscriptional — Gene Silencings, Posttranscriptional — RNA Silencing — Post-Transcriptional Gene Silencing — Post Transcriptional Gene Silencing — Post-Transcriptional Gene Silencings — Silencing, Post-Transcriptional Gene — Gene Silencing, Post-Transcriptional — Gene Silencing, Post Transcriptional — Cosuppression — Co-Suppression — Co Suppression