RNA, Small Interfering

siRNA

Engelsk definition

Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Interfering RNA, Small — siRNA — Small Interfering RNA — Short Interfering RNA — Interfering RNA, Short — RNA, Short Interfering — Scan RNA — RNA, Scan — scnRNA — Small Scan RNA — RNA, Small Scan — Scan RNA, Small — Repeat-Associated siRNA — Repeat Associated siRNA — siRNA, Repeat-Associated — siRNA, Repeat Associated — Trans-Acting siRNA — Trans Acting siRNA — siRNA, Trans-Acting — siRNA, Trans Acting — tasiRNA — Short Hairpin RNA — Hairpin RNA, Short — RNA, Short Hairpin — shRNA — Small Hairpin RNA — Hairpin RNA, Small — RNA, Small Hairpin