RNA, Small Interfering

siRNA

Engelsk definition

Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.

Svenska synonymer

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Engelska synonymer

Interfering RNA, Small Small Interfering RNA Short Interfering RNA Interfering RNA, Short RNA, Short Interfering siRNA Short Hairpin RNA Hairpin RNA, Short RNA, Short Hairpin Small Hairpin RNA Hairpin RNA, Small RNA, Small Hairpin shRNA Scan RNA scnRNA Small Scan RNA RNA, Small Scan Scan RNA, Small RNA, Scan Trans-Acting siRNA Trans Acting siRNA tasiRNA siRNA, Trans-Acting siRNA, Trans Acting Repeat-Associated siRNA Repeat Associated siRNA siRNA, Repeat-Associated siRNA, Repeat Associated