Svensk definition
Ett polymorft enzym som katalyserar hydroxyleringen av debrisokin. Det omsätter också ett flertal antidepressiva och neuroleptiska preparat. Enzymet uppvisar defekter hos ungefär 10% av befolkningen. EC 1.14.99.-.
Cytochrome P-450 CYP2D6
Cytokrom P-450 CYP2D6
Engelsk definition
A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
CYP2D6, Cytochrome P-450 — Cytochrome P 450 CYP2D6 — P-450 CYP2D6, Cytochrome — Sparteine Monooxygenase — Monooxygenase, Sparteine — Cytochrome P450 2D6 — P450 2D6, Cytochrome — Debrisoquine 4-Monooxygenase — 4-Monooxygenase, Debrisoquine — Debrisoquine 4 Monooxygenase — Imipramine 2-Hydroxylase — 2-Hydroxylase, Imipramine — Imipramine 2 Hydroxylase — CYP2D6 — CYP 2D6 — Debrisoquine 4-Hydroxylase — 4-Hydroxylase, Debrisoquine — Debrisoquine 4 Hydroxylase — Debrisoquine Hydroxylase — Hydroxylase, Debrisoquine