En peptid med 21 aminosyror som produceras i ett flertal vävnader, inklusive endotelceller, vaskulära muskelceller, nervceller och astrocyter i centrala nervsystemet, och endometrieceller. Den modulerar vasomotorisk spänning, cellproliferation och hormonproduktion.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
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Endothelin 1 — Endothelin Type 1 — Proendothelin (1-38) — Big Endothelin — Big Endothelin-1 — Big Endothelin 1 — Endothelin-1, Big — Endothelin, Big — Preproendothelin-1 — Preproendothelin 1 — Preproendothelin — Proendothelin-1 Precursor — Precursor, Proendothelin-1 — Proendothelin 1 Precursor