Platelet Glycoprotein GPIb-IX Complex

Trombocytglykoprotein GPIb-IX-komplex

Engelsk definition

Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.

Svenska synonymer

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Engelska synonymer

Platelet Glycoprotein GPIb IX Complex Glycoprotein Ib-IX Complex Glycoprotein Ib IX Complex Platelet Membrane Glycoprotein Ib Glycoprotein Ib Platelet Membrane Glycoprotein IX Platelet Glycoprotein IX CD42a Antigen Antigen, CD42a Antigens, CD42a CD42a Antigens Platelet Membrane Glycoprotein V CD42b Antigens Glycoprotein Ib alpha CD42b Antigen Antigen, CD42b Antigens, CD42b CD42c Antigens CD42c Antigen Antigen, CD42c Antigens, CD42c Glycoprotein Ib beta CD42d Antigen Antigen, CD42d Antigens, CD42d CD42d Antigens