Platelet Glycoprotein GPIb-IX Complex

Trombocytglykoprotein GPIb-IX-komplex

Engelsk definition

Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.

Svenska synonymer

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Engelska synonymer

Platelet Glycoprotein GPIb IX Complex Glycoprotein Ib-IX Complex Glycoprotein Ib IX Complex Platelet Membrane Glycoprotein Ib Glycoprotein Ib CD42c Antigens Glycoprotein Ib beta CD42c Antigen Antigen, CD42c Antigens, CD42c CD42b Antigens Antigens, CD42b Glycoprotein Ib alpha CD42b Antigen Antigen, CD42b Platelet Membrane Glycoprotein V CD42d Antigen Antigen, CD42d CD42d Antigens Antigens, CD42d Platelet Membrane Glycoprotein IX CD42a Antigens Antigens, CD42a Platelet Glycoprotein IX CD42a Antigen Antigen, CD42a