Svensk definition
Bildande av multipla proteinisoformer utifrån en enda gen. Alternativ splitsning innefattar sammanfogning av icke-konsekutiva exoner under tillkomsten av några, men inte alla, av genens transkript. En viss exon kan sålunda förenas med vilken som helst av flera andra exoner för att bilda budbärar-RNA. De alternativa formerna producerar proteiner som har en gemensam del och en avvikande del.
Engelsk definition
A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of EXONS during the processing of some, but not all, transcripts of the gene. Thus a particular exon may be connected to any one of several alternative exons to form a mature RNA. The alternative forms of mature MESSENGER RNA produce PROTEIN ISOFORMS in which one part of the isoforms is common while the other parts are different.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
Alternative Splicings — Splicings, Alternative — Alternate Splicing — Alternate Splicings — Splicing, Alternate — Splicings, Alternate — RNA Splicing, Alternative — Alternative RNA Splicing — Alternative RNA Splicings — RNA Splicings, Alternative — Splicing, Alternative RNA — Splicings, Alternative RNA — Splicing, Alternative — Nested Transcripts — Nested Transcript — Transcript, Nested — Transcripts, Nested