Proto-Oncogene Proteins c-abl

Proto-onkogenproteiner c-abl

Engelsk definition

Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

c-abl, Proto-Oncogene Proteins Proto Oncogene Proteins c abl abl Proto-Oncogene Products abl Proto Oncogene Products Products, abl Proto-Oncogene Proto-Oncogene Products, abl Proto-Oncogene Proteins abl abl, Proto-Oncogene Proteins Proteins abl, Proto-Oncogene Proto Oncogene Proteins abl abl Proto-Oncogene Proteins abl Proto Oncogene Proteins Proto-Oncogene Proteins, abl c-abl Proteins c abl Proteins