Engelsk definition
Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
Proto Oncogene Proteins c abl — c-abl, Proto-Oncogene Proteins — Proto-Oncogene Proteins abl — Proteins abl, Proto-Oncogene — Proto Oncogene Proteins abl — abl, Proto-Oncogene Proteins — c-abl Proteins — c abl Proteins — abl Proto-Oncogene Products — Products, abl Proto-Oncogene — Proto-Oncogene Products, abl — abl Proto Oncogene Products — abl Proto-Oncogene Proteins — Proto-Oncogene Proteins, abl — abl Proto Oncogene Proteins