Receptors, Leukocyte-Adhesion

Receptorer, leukocytadhesion

Engelsk definition

Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Receptors, Leukocyte Adhesion Leukocyte-Adhesion Receptor Leukocyte Adhesion Receptor Receptor, Leukocyte-Adhesion Leukocyte-Adhesion Receptor Family Leukocyte Adhesion Receptor Family Leu-CAM Receptor Family Family, Leu-CAM Receptor Leu CAM Receptor Family Receptor Family, Leu-CAM Leukocyte-Adhesion Receptors Leukocyte Adhesion Receptors