Inositol 1,4,5-Trisphosphate

Inositol-1,4,5-trifosfat

Svensk definition

En intracellulär budbärare som bildas genom verkan av fosfolipas C på fosfatidylinositol-4,5-bifosfat, en av de fosfolipider som bygger upp cellmembranet. Inositol-1,4,5-trifosfat frisätts i cytoplasman, där det frigör kalciumjoner som finns lagrade i cellens endoplasmatiska retikel. Dessa kalciumjoner stimulerar verkan av B-kinas eller kalmodulin.

Engelsk definition

Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Inositol 1,4,5-Triphosphate Myoinositol 1,4,5-Triphosphate 1,4,5-InsP3 1,4,5-IP3 Myo-Inositol 1,4,5-Trisphosphate