An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
CYP21
Cytochrome P-450 21-Hydroxylase — Cytochrome P 450 21 Hydroxylase — Cytochrome P-450(c-21) — Progesterone 21-Hydroxylase — Progesterone 21 Hydroxylase — Cytochrome P-450 CYP21 — Cytochrome P 450 CYP21 — Steroid 21-Monooxygenase — Steroid 21 Monooxygenase — Cytochrome P450c21 — Cytochrome P-450 c21 — Cytochrome P 450 c21 — P-450 c21, Cytochrome — 21-Hydroxylase — 21 Hydroxylase — Steroid-21-Hydroxylase — Steroid 21 Hydroxylase