Leucyl Aminopeptidase

Leucylaminopeptidas

Svensk definition

Ett zinkhaltigt enzym av hydrolasklassen som katalyserar frånkopplingen av den aminosyra som utgör N-terminalen hos de flesta L-peptider, i synnerhet sådana vars N-terminal har leucin som restsekvens, men inte dem med lysin eller arginin. Denna process äger rum i vävnadscellscytosol, med hög aktivitet i tolvfingertarmen, levern och njurarna. EC 3.4.11.1.

Engelsk definition

A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. This occurs in tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate such as leucyl beta-naphthylamide.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Aminopeptidase, Leucyl L-Leucylnaphthylamidase Zinc-Manganese-Leucine Aminopeptidase Aminopeptidase, Zinc-Manganese-Leucine Zinc Manganese Leucine Aminopeptidase Peptidase S Cytosol Aminopeptidase Aminopeptidase, Cytosol Leucine Aminopeptidase Aminopeptidase, Leucine Methoxyleucine Aminopeptidase Aminopeptidase, Methoxyleucine