Ett enzym som katalyserar nedbrytningen av insulin, glukagon och andra polypeptider. Det hämmas av bacitracin, de kelerande ämnena EDTA och 1,10-fenantrolin och tiolblockerande reagentia som t ex N-etylmaleimid, men inte fosforamidon. EC 3.4.24.56.
An enzyme the catalyzes the degradation of insulin, glucagon and other polypeptides. It is inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and by thiol-blocking reagents such as N-ethylmaleimide, but not phosphoramidon. (Eur J Biochem 1994;223:1-5) EC 3.4.24.56.
Insulinas
Insulin-Degrading Enzyme — Enzyme, Insulin-Degrading — Insulin Degrading Enzyme — Insulin Protease — Protease, Insulin — Insulin Proteinase — Proteinase, Insulin — Insulinase