Svensk definition
Hämmare av enzymet dihydrofolatreduktas (tetrahydrofolatdehydrogenas), som omvandlar dihydrofolat (FH2) till tetrahydrofolat (FH4). De har utbredd användning inom cancerkemoterapi.
Folic Acid Antagonists
Folsyraantagonister
Engelsk definition
Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033)
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
Acid Antagonists, Folic — Antagonists, Folic Acid — Antifolate — Dihydrofolate Reductase Inhibitors — Inhibitors, Dihydrofolate Reductase — Reductase Inhibitors, Dihydrofolate — Antifolates — Folic Acid Antagonist — Acid Antagonist, Folic — Antagonist, Folic Acid — Dihydrofolate Reductase Inhibitor — Inhibitor, Dihydrofolate Reductase — Reductase Inhibitor, Dihydrofolate — Folic Acid Metabolism Inhibitors