Svensk definition
Blodkoagulationsfaktor VIII, en antihemofilifaktor som utgör en del av faktor VIII/von Willebrandfaktorkomplexet. Faktor VIII produceras i levern och har sin verkan i den inre koagulationsprocessen. Den tjänar som kofaktor vid faktor X-aktivering, vilken påtagligt förstärks genom små mängder trombin.
Engelsk definition
Factor VIII of blood coagulation. Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin.
Svenska synonymer
Hemofil M — Monoclate — Koagulationsfaktor VIII — Antihemofil faktor A
Engelska synonymer
Factor 8 — Coagulation Factor VIII — Thromboplastinogen — Blood Coagulation Factor VIII — Factor Eight — Hyatt-C — Hyatt C — HyattC — Hyate-C — Hyate C — HyateC — Factor VIIIC — Factor 8 C — F VIII-C — F VIII C — Factor VIII Coagulant Antigen — Factor VIII Clotting Antigen — Factor VIII Procoagulant Activity