Chlorambucil

Klorambucil

Svensk definition

En alkylerande kvävesenap som används som antitumörmedel (cytostatikum) vid kronisk lymfatisk leukemi, Hodgkins sjukdom m fl. Även om den är mindre giftig än flertalet kvävesenapsformer, så har medlet tagits upp som känd karcinogen i Fourth report on carcinogens (NTP 85-002, 1985).

Engelsk definition

A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)

Svenska synonymer

Leukeran

Engelska synonymer

4-(Bis(2-chloroethyl)amino)benzenebutanoic Acid N,N-Di-(2-chloroethyl)-p-aminophenylbutyric Acid Chloraminophene Chlorbutin NSC-3088 NSC 3088 NSC3088 Leukeran Lympholysin Amboclorin CB-1348 CB 1348 CB1348