Antithrombins

Antitrombiner

Svensk definition

En endogen familj av proteiner tillhörande serpinsuperfamiljen som neutraliserar effekterna av trombin. Sex naturligt förekommande antitrombiner har identifierats och betecknas med de romerska siffror na I - VI. Antitrombin I och III tycks vara de med störst betydelse.

Engelsk definition

Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.

Svenska synonymer

Trombinhämmare

Engelska synonymer

Direct Antithrombin Antithrombin, Direct Direct Antithrombins Antithrombins, Direct Direct Thrombin Inhibitors Thrombin Inhibitors, Direct Direct Thrombin Inhibitor Inhibitor, Direct Thrombin Thrombin Inhibitor, Direct Antithrombin