Förutom sin antiinflammatoriska verkan har dessa preparat också smärtstillande och febernedsättande effekt. De används främst vid kronisk artrit och vissa tillstånd med smärtande och inflammerad mjuk vävnad. De blockerar prostaglandinsyntesen genom att hämma cyklooxygenas, som omvandlar arakidonsyra till cykliska endoperoxider.
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
NSAID — Antiinflammatoriska smärtstillande medel — Antiinflammatoriska medel, icke-steroida
NSAID — Nonsteroidal Anti-Inflammatory Agent — Agent, Nonsteroidal Anti-Inflammatory — Anti-Inflammatory Agent, Nonsteroidal — Nonsteroidal Anti Inflammatory Agent — NSAIDs — Antiinflammatory Agents, Non Steroidal — Antiinflammatory Agents, Nonsteroidal — Nonsteroidal Antiinflammatory Agents — Non-Steroidal Anti-Inflammatory Agents — Non Steroidal Anti Inflammatory Agents — Nonsteroidal Anti-Inflammatory Agents — Nonsteroidal Anti Inflammatory Agents — Non-Steroidal Anti-Inflammatory Agent — Agent, Non-Steroidal Anti-Inflammatory — Anti-Inflammatory Agent, Non-Steroidal — Non Steroidal Anti Inflammatory Agent — Anti Inflammatory Agents, Nonsteroidal — Analgesics, Anti-Inflammatory — Anti-Inflammatory Analgesics — Aspirin-Like Agents — Aspirin Like Agents — Aspirin-Like Agent — Agent, Aspirin-Like — Aspirin Like Agent