Degrons

Engelsk definition

Minimal elements within a protein that are sufficient for recognition and degradation by a proteolytic apparatus. Inherent degrons are comprised of short linear amino acid sequences and secondary protein structural features that increase the affinity to E3 LIGASE; and are involved in regulating the specificity and timing of PROTEIN DEGRADATION. Acquired degrons are mostly transient and conferred by post-translational modifications of specific amino acids within proteins. (From Mol Cell. 2016 Sep 15;63(6):1055-65)

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Degron — C-Degrons — C Degrons — C-Degron — PEST Motif — Motif, PEST — Motifs, PEST — PEST Motifs — PEST Sequence — PEST Sequences — Sequence, PEST — Sequences, PEST — Destruction Box Motif — Box Motif, Destruction — Box Motifs, Destruction — Destruction Box Motifs — Motif, Destruction Box — Motifs, Destruction Box — D-Box Motif — D Box Motif — D-Box Motifs — Motif, D-Box — Motifs, D-Box — Destruction Boxes — Destruction Box — N-Degrons — N Degrons — N-Degron