Engelsk definition
A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue from a distinct range of substrates. The catalytic efficiency is 400-fold higher with ANGIOTENSIN II as a substrate than with ANGIOTENSIN I. Angiotensin-converting enzyme 2 is also is a functional receptor for the spike glycoprotein (SPIKE PROTEIN, CORONAVIRUS) of the CORONAVIRUSES SARS-COV, SARS-COV2, and HCOV-NL63.
Svenska synonymer
ACE2-protein — ACE2-enzym — ACE-relaterat karboxypeptidas
Engelska synonymer
Angiotensin Converting Enzyme 2 — ACE2 Protein — ACE2 Angiotensin-Converting Enzyme Protein 2 — ACE2 Angiotensin Converting Enzyme Protein 2 — ACE-Related Carboxypeptidase — ACE Related Carboxypeptidase — Carboxypeptidase, ACE-Related — Angiotensin-Converting Enzyme-Related Carboxypeptidase — Angiotensin Converting Enzyme Related Carboxypeptidase — Carboxypeptidase, Angiotensin-Converting Enzyme-Related — ACE2 Enzyme